Shebindu Intelligent Microphysiological Systems Laboratory
Integrating microengineering, immunology, and translational medicine to build intelligent human-on-a-chip systems that model immune cell dynamics across multiple organs.
Our interdisciplinary approach combines three core domains to create breakthrough microphysiological systems
Automated microfluidics, organ-on-a-chip systems, machine learning integration, and advanced biomaterials for next-generation microphysiological platforms.
Leukocyte biology, inflammation pathways, cytokine signaling networks, and immune system dynamics in health and disease states.
Autoimmune disease modeling, systemic inflammation research, drug screening platforms, and patient-specific diagnostic tools for clinical applications.
To lead breakthrough research in intelligent human-on-a-chip systems that revolutionize our understanding of immune dynamics and organ interactions, ultimately improving global health outcomes.
We envision a future where microphysiological systems serve not only as drug screening tools but as comprehensive discovery platforms that decode the complex relationships between immunity, inflammation, and organ function.
Model how immune cells dynamically interact with vascular and organ-specific tissues across multiple organs
Study both homeostatic and pathological conditions to understand disease progression mechanisms
Uncover how local inflammation leads to systemic dysfunction across various disease states
Map immune dynamics, decode organ-organ crosstalk, and test patient-specific interventions
Design modular and frugally engineered systems for deployment in diverse global health settings
Bridge laboratory discoveries to real-world clinical applications and therapeutic development
Transforming research discoveries into real-world healthcare solutions across multiple disease domains
Model pathogen-host interactions and immune responses to develop new therapeutic strategies
Study tumor-immune microenvironments to advance personalized cancer treatment approaches
Investigate immune complications in patients with mechanical circulatory support devices
Accelerate pharmaceutical development with more predictive human-relevant screening platforms
Enable patient-specific disease modeling and therapeutic intervention testing
Deploy accessible diagnostic and research tools in resource-limited healthcare settings
Our systems serve as comprehensive discovery tools that map immune dynamics, decode organ-organ crosstalk, and enable testing of patient-specific interventions. We emphasize technological innovation alongside accessibility, creating modular platforms that can be deployed globally.
We are building the future of microphysiological systems and translational medicine. Connect with us to explore collaboration opportunities, research partnerships, or join our team.